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Comment
. 2010 Oct 13;18(10):1222-3.
doi: 10.1016/j.str.2010.09.002.

The talin FERM domain is not so FERM

Iain D Campbell  1
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The talin FERM domain is not so FERM

Iain D Campbell. Structure. .
Free article

Abstract

The structure of the head domain of talin, an intracellular activator of integrin membrane adhesion receptors, has been solved by Elliott et al. (2010). A FERM domain can be identified in the head from sequence comparisons but, rather than having a compact structure of three subdomains, it has linear arrangement of four subdomains.

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