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. 2009 May 28:1:40.
doi: 10.3410/B1-40.

New antibiotics for antibiotic-resistant bacteria

Affiliations

New antibiotics for antibiotic-resistant bacteria

William Stubbings et al. F1000 Biol Rep. .

Abstract

The need for new antibiotics to effectively treat antibiotic-resistant infections remains unfulfilled. Despite the well-publicised concern over this issue, only two novel antibiotic classes have been introduced in the past 20 years alongside several new agents of existing classes. Accordingly, the current antibiotic armoury remains inadequate to meet the challenges posed by resistance today. More worryingly, there are very few new agents being developed that can be expected to replace existing antibiotics that succumb to the rising tide of resistance.

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References

    1. Boucher HW, Talbot GH, Bradley JS, Edwards JE, Jr, Gilbert D, Rice LB, Scheld M, Spellberg B, Bartlett J. Bad bugs, no drugs: No ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis. 2009;48:1–12. doi: 10.1086/595011. - DOI - PubMed
    1. Stryjewski ME, Chambers HF. Skin and soft-tissue infections caused by community-acquired methicillin-resistant Staphylococcus aureus. Clin Infect Dis. 2008;46(5):S368–77. doi: 10.1086/533593. - DOI - PubMed
    1. Jassal M, Bishai WR. Extensively drug-resistant tuberculosis. Lancet Infect Dis. 2009;9:19–30. doi: 10.1016/S1473-3099(08)70260-3. - DOI - PubMed
    1. South San Francisco, CA, USA: Theravance; Feb 26, 2009. Theravance receives complete response letter on the telavancin new drug application for the treatment of cSSSI [press release]
    1. Arias CA, Murray BE. Emergence and management of drug-resistant enterococcal infections. Expert Rev Anti Infect Ther. 2008;6:637–55. doi: 10.1586/14787210.6.5.637. - DOI - PubMed