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. 2010 Feb 24:2:14.
doi: 10.3410/M2-14.

Genetic screening for multiple endocrine neoplasia syndrome type 1 (MEN-1): when and how

Alberto Falchetti  1
Affiliations

Genetic screening for multiple endocrine neoplasia syndrome type 1 (MEN-1): when and how

Alberto Falchetti. F1000 Med Rep. .

Abstract

Multiple endocrine neoplasia syndrome type 1 (MEN1) syndrome has benefited from the identification of the gene whose mutations account for the genetic susceptibility to develop endocrine tumors. Asymptomatic MEN1 mutant carriers need to be clearly recognized because the gene-related mutations confer a high risk of multiple primary cancers, occur at younger ages, and affect multiple family members who inherit the cancer-predisposing genetic mutation.

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Figures

Figure 1.
Figure 1.. Algorithmic summary of the diagnostic protocols
MEN1, multiple endocrine neoplasia syndrome type 1.
See this image and copyright information in PMC

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