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Comment
. 2010 Oct 19;19(4):485-6.
doi: 10.1016/j.devcel.2010.10.003.

Linc-ing Long noncoding RNAs and enhancer function

John S Mattick  1
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Free article
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Linc-ing Long noncoding RNAs and enhancer function

John S Mattick. Dev Cell. .
Free article

Abstract

Enhancers are distal regulatory sequences that control gene expression in development. Ørom et al. now report in Cell that some long noncoding RNAs have functional properties of enhancers. Known enhancers are also transcribed in cells in which they are active, suggesting that noncoding RNAs are integral to enhancer action.

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  • Long noncoding RNAs with enhancer-like function in human cells.
    Ørom UA, Derrien T, Beringer M, Gumireddy K, Gardini A, Bussotti G, Lai F, Zytnicki M, Notredame C, Huang Q, Guigo R, Shiekhattar R. Ørom UA, et al. Cell. 2010 Oct 1;143(1):46-58. doi: 10.1016/j.cell.2010.09.001. Cell. 2010. PMID: 20887892 Free PMC article.

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