How the sea squirt nucleus tells mesoderm not to be endoderm
- PMID: 20951340
- PMCID: PMC3232446
- DOI: 10.1016/j.devcel.2010.10.002
How the sea squirt nucleus tells mesoderm not to be endoderm
Abstract
Sea squirts are simple invertebrate chordates. In this issue of Developmental Cell, Takatori et al. show nuclear migration within ascidian mesendodermal cells enables polarized localization of Not mRNA, which encodes a homeobox protein that distinguishes mesoderm from endoderm fates. The link between nuclear migration and mRNA localization suggests exciting parallels with protostomes.
Copyright © 2010 Elsevier Inc. All rights reserved.
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Segregation of germ layer fates by nuclear migration-dependent localization of Not mRNA.Dev Cell. 2010 Oct 19;19(4):589-98. doi: 10.1016/j.devcel.2010.09.003. Dev Cell. 2010. PMID: 20951349
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Segregation of germ layer fates by nuclear migration-dependent localization of Not mRNA.Dev Cell. 2010 Oct 19;19(4):589-98. doi: 10.1016/j.devcel.2010.09.003. Dev Cell. 2010. PMID: 20951349
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