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. 2010 Oct 19;19(4):489-90.
doi: 10.1016/j.devcel.2010.10.001.

Stem cell fate in proliferating tissues: equal odds in a game of chance

Philip H Jones  1
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Stem cell fate in proliferating tissues: equal odds in a game of chance

Philip H Jones. Dev Cell. .
Free article

Abstract

Quantitative lineage tracing reveals stem cell fate in vivo. A new study in a recent issue of Cell shows intestinal crypt stem cells are functionally equivalent, with equal odds of differentiation. Differentiating stem cells are replaced by the symmetric division of adjacent stem cells.

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