Gas-diffusion microextraction

Abstract

Gas-diffusion microextraction (GDME) is an innovative technique that combines the advantages of membrane-aided gas-diffusion with microextraction concepts. GDME makes uses of a novel portable and low-cost device that comprises a small, commercially available, semi-permeable membrane. Furthermore, if derivatization is integrated into the GDME concept, considerable enrichment factors can be obtained. It may become a powerful tool for any analyst who intends to quantify volatile and semi-volatile analytes in various kinds of matrices. The analysis of vicinal diketones in beer was used as a case study to show GDME applicability and capabilities. Vicinal diketones were derivatized with o-phenylenediamine and then determined by HPLC-UV. Obtained results showed good repeatability and precision with extraction periods at the minute time span.