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Case Reports
. 2010 Jun;19(116):165-8.
doi: 10.1183/09059180.00001310.

Talcosis due to abundant use of cosmetic talcum powder

A van Huisstede, V Noordhoek Hegt, I Otte-Holler, M Looijen-Salamon, A Rudolphus
Case Reports

Talcosis due to abundant use of cosmetic talcum powder

A van Huisstede et al. Eur Respir Rev. 2010 Jun.
No abstract available

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Figures

FIGURE 1.
FIGURE 1.
Radiodiagnostic imaging. a) A chest radiograph showing multiple nodular lesions in both lungs. b) A high-resolution computed tomography scan showing a diffuse nodular image in both lungs. Interlobular septa and pleura were normal.
FIGURE 2.
FIGURE 2.
Transbronchial lung biopsy microscopic slide of a) lung tissue showing a granulomatous inflammation with giant cell reaction and b) lung tissue under polarised light (birefringed crystalline material). c) Scanning transmission electron micrograph of the lung biopsy specimen showing sheets and fibres. In this area five different points were selected with the point and shoot utility. Points 1–4: electron dense crystalline material; point 5: control area. Scale bar = 100 nm. d) Energy-dispersive spectroscopy spectrum of point 1, all crystals in the lung biopsy specimen showed peaks for magnesium (Mg) and silicon (Si) in a ratio consistent with talc. Reference measurements such as point 5, however, showed only peaks for copper (Cu), originating from the copper carrier grid.
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