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Case Reports
. 2010 Oct 5:4:1081-4.
doi: 10.2147/OPTH.S13730.

Choroidal osteoma with choroidal neovascular membrane: Successful treatment with intravitreal bevacizumab

Neeraj Pandey  1 , Ayachit Guruprasad
Affiliations
Case Reports

Choroidal osteoma with choroidal neovascular membrane: Successful treatment with intravitreal bevacizumab

Neeraj Pandey et al. Clin Ophthalmol. .

Abstract

An otherwise healthy 27-year-old woman presented with complaints of sudden painless blurred vision in the right eye for one week. On examination, visual acuity was 20/30 in the right eye and 20/20 in left eye. Fundus examination OS was normal, but OD demonstrated an elevated, opaque, yellowish parapapillary choroidal lesion with grayish membrane associated with minimal subretinal fluid, suggestive of a choroidal neovascular membrane in the center. B-scan ultrasonography revealed findings consistent with a choroidal osteoma. Fundus fluorescein angiography of the right eye revealed a relatively well defined area of hyperfluorescence that increased in size and intensity in the later phases, suggestive of active extrafoveal choroidal neovascular membrane. Optical coherence tomography confirmed the extrafoveal choroidal neovascular membrane with subfoveal fluid. She was treated with intravitreal bevacizumab OD. At the two-week visit, vision OD improved to 20/20. Fluorescein angiography and optical coherence tomography revealed a resolved choroidal neovascular membrane. Intravitreal bevacizumab may be an effective alternative in the management of choroidal neovascular membrane secondary to choroidal osteoma.

Keywords: bevacizumab; choroidal neovascular membrane; optical coherence tomography; osteoma.

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Figures

Figure 1
Figure 1
Fluorescein angiography and optical coherence tomography showing corresponding location of choroidal neovascular membrane associated with osteoma in right eye.
Figure 2
Figure 2
Fluorescein angiography of right eye showing early lacy hyperfluorescence of choroidal neovascular membrane with later leakage, and B-scan (80 dB) showing corresponding shadowing due to osteoma.
Figure 3
Figure 3
Absence of subfoveal fluid on optical coherence tomography with regressed choroidal neovascular membrane.
Figure 4
Figure 4
Fluorescein angiography showing regressed choroidal neovascular membrane with no leakage (early, middle, and late phase in the clockwise direction).
Figure 5
Figure 5
OCT maps comparison showing reduction in thickness.
See this image and copyright information in PMC

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