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Review
. 2010 Sep 15;11(9):3298-322.
doi: 10.3390/ijms11093298.

Materials for pharmaceutical dosage forms: molecular pharmaceutics and controlled release drug delivery aspects

Heidi M Mansour  1 , Minji Sohn, Abeer Al-Ghananeem, Patrick P Deluca
Affiliations
Review

Materials for pharmaceutical dosage forms: molecular pharmaceutics and controlled release drug delivery aspects

Heidi M Mansour et al. Int J Mol Sci. .

Abstract

Controlled release delivery is available for many routes of administration and offers many advantages (as microparticles and nanoparticles) over immediate release delivery. These advantages include reduced dosing frequency, better therapeutic control, fewer side effects, and, consequently, these dosage forms are well accepted by patients. Advances in polymer material science, particle engineering design, manufacture, and nanotechnology have led the way to the introduction of several marketed controlled release products and several more are in pre-clinical and clinical development.

Keywords: biodegradable; biomaterials; copolymers; manufacture; microparticle; nanoparticle; particle engineering design; pharmaceutical dosage forms; polymers.

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Figures

Figure 1
Figure 1
Structures of biodegradable and biocompatible polymers.
Figure 2
Figure 2
Various therapeutic agents from different therapeutic classes that have been encapsulated in polymeric particles.
See this image and copyright information in PMC

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