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Review
. 2010 Nov;49(11):1351-5.
doi: 10.1007/s00120-010-2394-5.

[Early detection of prostate cancer: is serum PSA testing alone sufficient?]

[Article in German]
C Börgermann  1 , F Vom Dorp, G Breuer, S Kliner, H Rübben
Affiliations
Review

[Early detection of prostate cancer: is serum PSA testing alone sufficient?]

[Article in German]
C Börgermann et al. Urologe A. 2010 Nov.

Abstract

The euphoria over PSA as an optimal marker for prostate cancer is gone. Measuring PSA levels has several deficiencies in detecting prostate cancer. First results of the randomized studies ERSPC and PLCO were not able to conclusively prove the value of PSA-based screening. Many attempts have been made to optimize early detection of prostate cancer like using modern imaging techniques or new biomarkers. This review deals with PSA isoforms und emerging biomarkers for the diagnosis of prostate cancer. Despite the inadequacies of PSA it is still the most important marker for the early detection of prostate cancer. Modern biomarkers with the ability to reliably predict aggressive prostate cancer are still missing.

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References

    1. N Engl J Med. 2009 Mar 26;360(13):1310-9 - PubMed
    1. Eur Urol. 2003 Jul;44(1):8-15; discussion 15-6 - PubMed
    1. Urologe A. 1993 May;32(3):250-3 - PubMed
    1. J Urol. 2010 Feb;183(2):534-8 - PubMed
    1. J Urol. 1994 May;151(5):1283-90 - PubMed

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