Review
doi: 10.1016/S0929-6646(10)60112-X.
HTLV-1 and adult T-cell leukemia: insights into viral transformation of cells 30 years after virus discovery
Affiliations
- PMID: 20970064
- DOI: 10.1016/S0929-6646(10)60112-X
Item in Clipboard
Review
HTLV-1 and adult T-cell leukemia: insights into viral transformation of cells 30 years after virus discovery
J Formos Med Assoc.
2010 Oct.
Free article
Abstract
Human T-cell leukemia virus type 1 (HTLV-1), the etiological agent of adult T-cell leukemia, was the first human retrovirus to be isolated. It is now the 30(th) anniversary of the initial discovery of HTLV-1. This review discusses recent insights into the role of the HTLV-1 Tax oncoprotein in cellular proliferation and the abrogation of cellular checkpoints that lead to disease progression.
Copyright © 2010 Formosan Medical Association & Elsevier. Published by Elsevier B.V. All rights reserved.
Similar articles
-
HTLV-1 Tax and adult T-cell leukemia.Front Biosci. 2007 Jan 1;12:1496-507. doi: 10.2741/2163. Front Biosci. 2007. PMID: 17127397 Review.
-
HTLV-1 Tax: Linking transformation, DNA damage and apoptotic T-cell death.Chem Biol Interact. 2010 Nov 5;188(2):359-65. doi: 10.1016/j.cbi.2010.06.005. Epub 2010 Jun 15. Chem Biol Interact. 2010. PMID: 20558150 Review.
-
Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells.Cancer Sci. 2015 Apr;106(4):461-5. doi: 10.1111/cas.12618. Epub 2015 Mar 16. Cancer Sci. 2015. PMID: 25613934 Free PMC article.
-
[Adult T-cell leukemia induced by HTLV-1: before and after HBZ].Med Sci (Paris). 2010 Apr;26(4):391-6. doi: 10.1051/medsci/2010264391. Med Sci (Paris). 2010. PMID: 20412744 Review. French.
-
Inducible nitric oxide synthase mediates DNA double strand breaks in Human T-Cell Leukemia Virus Type 1-induced leukemia/lymphoma.Retrovirology. 2015 Aug 12;12:71. doi: 10.1186/s12977-015-0196-y. Retrovirology. 2015. PMID: 26265053 Free PMC article.
Cited by
-
MicroRNAs and human retroviruses.Biochim Biophys Acta. 2011 Nov-Dec;1809(11-12):686-93. doi: 10.1016/j.bbagrm.2011.05.009. Epub 2011 May 24. Biochim Biophys Acta. 2011. PMID: 21640212 Free PMC article. Review.
-
Human T-cell leukemia virus type 1 (HTLV-1) Tax1 oncoprotein but not HTLV-2 Tax2 induces the expression of OX40 ligand by interacting with p52/p100 and RelB.Virus Genes. 2016 Feb;52(1):4-13. doi: 10.1007/s11262-015-1277-7. Epub 2016 Jan 6. Virus Genes. 2016. PMID: 26739459
-
Prevalence and evolutionary analyses of human T-cell lymphotropic virus in Guangdong province, China: Transcontinental and Japanese subtype lineages dominate the prevalence.PLoS Negl Trop Dis. 2021 Feb 4;15(2):e0009043. doi: 10.1371/journal.pntd.0009043. eCollection 2021 Feb. PLoS Negl Trop Dis. 2021. PMID: 33539355 Free PMC article.
-
Adaptive immune response to viral infections in the central nervous system.Handb Clin Neurol. 2014;123:225-47. doi: 10.1016/B978-0-444-53488-0.00010-9. Handb Clin Neurol. 2014. PMID: 25015488 Free PMC article.
-
Cell surface markers in HTLV-1 pathogenesis.Viruses. 2011 Aug;3(8):1439-59. doi: 10.3390/v3081439. Epub 2011 Aug 16. Viruses. 2011. PMID: 21994790 Free PMC article. Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
