Regulation between survival, persistence, and elimination of intracellular mycobacteria: a nested equilibrium of delicate balances
- PMID: 20971210
- DOI: 10.1016/j.micinf.2010.10.009
Regulation between survival, persistence, and elimination of intracellular mycobacteria: a nested equilibrium of delicate balances
Abstract
This review elaborates on recent insights gained on the dynamic aspects of interactions between pathogen and the host intracellular machinery in tuberculosis infection. In addition we will also discuss the utility of adopting a systems biology approach, both for a better understanding of TB biology, and for the development of more effective ways for disease management.
© 2010 Institut Pasteur. Published by Elsevier SAS. All rights reserved.
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