Pain in neonates is different
- PMID: 20971562
- DOI: 10.1016/j.pain.2010.10.008
Pain in neonates is different
Abstract
Pain processing and management in neonates, especially preterm neonates, differs from older populations. In this review, a brief background on pain processing in neonatal life, pain exposure in Neonatal Intensive Care Units (NICU), the consequences of untreated pain, and the difficulties in treating procedural pain pharmacologically will be presented. A more detailed review of non-pharmacological interventions for procedural pain in neonates will include sensory stimulation approaches, oral sweet solutions, and maternal interventions. Some possible mechanisms for the effectiveness of non-pharmacological interventions are offered. Finally, avenues of research into similar interventions as adjuvant therapies or drug-sparing effects in older populations are suggested.
Copyright © 2010 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.
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References
-
- Akcam M, Ormeci AR. Oral hypertonic glucose spray: a practical alternative for analgesia in the newborn. Acta Paediatr. 2004;93:1330-1333.
-
- Akcan E, Yigit R, Atici A. The effect of kangaroo care on pain in premature infants during invasive procedures. Turk J Pediatr. 2009;51:14-18.
-
- Allegaert K, Simons SH, Vanhole C, Tibboel D. Developmental pharmacokinetics of opioids in neonates. [Review] [31 refs.]. J Opioid Manag. 2007;3:59-64.
-
- Als H, Duffy FH, McAnulty G. Behavioural differences between preterm and fullterm newborns as measured with the APIB system scores: I. Infant Behav Dev. 1988;11:305-318.
-
- Anand KJ, Garg S, Rovnaghi CR, Narsinghani U, Bhutta AT, Hall RW. Ketamine reduces the cell death following inflammatory pain in newborn rat brain. Pediatr Res. 2007;62:283-290.