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. 2010 Nov;42(11):1027-30.
doi: 10.1038/ng.684. Epub 2010 Oct 24.

Genome-wide patterns of genetic variation among elite maize inbred lines

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Genome-wide patterns of genetic variation among elite maize inbred lines

Jinsheng Lai et al. Nat Genet. 2010 Nov.

Abstract

We have resequenced a group of six elite maize inbred lines, including the parents of the most productive commercial hybrid in China. This effort uncovered more than 1,000,000 SNPs, 30,000 indel polymorphisms and 101 low-sequence-diversity chromosomal intervals in the maize genome. We also identified several hundred complete genes that show presence/absence variation among these resequenced lines. We discuss the potential roles of complementation of presence/absence variations and other deleterious mutations in contributing to heterosis. High-density SNP and indel polymorphism markers reported here are expected to be a valuable resource for future genetic studies and the molecular breeding of this important crop.

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