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. 2011 Jan;17(1):58-60.
doi: 10.1016/j.parkreldis.2010.10.002. Epub 2010 Oct 25.

Handedness and dominant side of symptoms in Parkinson's disease

Anouk van der Hoorn  1 , Anna L Bartels, Klaus L Leenders, Bauke M de Jong
Affiliations

Handedness and dominant side of symptoms in Parkinson's disease

Anouk van der Hoorn et al. Parkinsonism Relat Disord. 2011 Jan.

Abstract

The aim of this retrospective study was to assess the presence of a possible association between handedness and the side of symptom dominance in 963 patients with Parkinson's disease (PD). In only 287 patients the hand dominance was registered. Out of 254 right-handed patients, 158 (62%) had a right-side dominance of PD symptoms, while 96 patients (38%) had left-lateralized symptom dominance (p < 0.001). For the 33 left-handed subjects, 18 (55%) had left- and 15 (45%) had right-sided symptom dominance (p = 0.602). Right-handedness thus appeared to be associated with right-sided dominance of PD symptoms, while the group of left-handed patients was too small to draw conclusions from. Possible explanations are discussed.

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