Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2010 Nov;161(6):1204-16.
doi: 10.1111/j.1476-5381.2010.01019.x.

Reflections on drug research

Affiliations

Reflections on drug research

James Black. Br J Pharmacol. 2010 Nov.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
The chemical structure of isoprenaline – the starting point of the quest for a beta blocker.
Figure 2
Figure 2
The chemical structure of cimetidine (Tagamet®).

Comment in

References

    1. Ahlquist RP. A study of the adrenotropic receptors. Am J Physiology. 1948;153:586–599. - PubMed
    1. Ahlquist RP. Adrenergic receptors: a personal and practical view. Perspectives Biol Med. 1973;3:119–122. - PubMed
    1. Ariens EJ. Affinity and intrinsic activity in the theory of competitive inhibition. Arch Int Pharmacodyn Ther. 1954;99:32–49. - PubMed
    1. Bayliss WM, Starling EH. The mechanism of pancreatic secretion. J Physiol. 1902;25–5:325–353. - PMC - PubMed
    1. Black JW. Reflections on some pilot trials of gastrin receptor blockade in pancreatic cancer. Eur J Cancer. 2009;45–3:360–365. - PubMed

Publication types

Substances