Small RNAs: The enigma of Prozac resolved
- PMID: 20979321
- DOI: 10.1038/nrn2941
Small RNAs: The enigma of Prozac resolved
Abstract
SSRIs are used to treat depression and have a delayed onset of action. The mechanism involves post-transcriptional regulation of a serotonin transporter in the raphe nucleus and the locus coeruleus.
Comment on
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miR-16 targets the serotonin transporter: a new facet for adaptive responses to antidepressants.Science. 2010 Sep 17;329(5998):1537-41. doi: 10.1126/science.1193692. Science. 2010. PMID: 20847275
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