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Review
. 1990 Jul;15(7):273-6.
doi: 10.1016/0968-0004(90)90053-e.

Histone H1 and the regulation of transcription of eukaryotic genes

J Zlatanova  1
Affiliations
Review

Histone H1 and the regulation of transcription of eukaryotic genes

J Zlatanova. Trends Biochem Sci. 1990 Jul.

Abstract

Histone H1 plays a role in the formation of chromatin structure, both at the level of the nucleosome particle itself and in the formation of the higher-order structures of the chromatin fibre. Histone H1 is regarded as a part of a general repressor mechanism that ensures a strong and stable repression of gene expression. In addition to serving as a general repressor for relatively large chromatin fragments, histone H1 might also be involved in controlling the transcriptional activity of individual genes.

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Comment in

  • Histone H1 and transcription.
    Daneholt B, Grossbach U. Daneholt B, et al. Trends Biochem Sci. 1990 Dec;15(12):463. doi: 10.1016/0968-0004(90)90298-p. Trends Biochem Sci. 1990. PMID: 2077684 No abstract available.

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