Review
doi: 10.1016/j.jvir.2010.08.009.
Epub 2010 Oct 27.
Angiogenesis and current antiangiogenic strategies for the treatment of cancer
Affiliations
- PMID: 20980167
- DOI: 10.1016/j.jvir.2010.08.009
Item in Clipboard
Review
Angiogenesis and current antiangiogenic strategies for the treatment of cancer
J Vasc Interv Radiol.
2010 Dec.
Abstract
Angiogenesis is a complex process critical for embryonic development and for survival. It is also a critical player in many pathologic processes, most notably in neoplasia. The cell signaling pathways involved in angiogenesis have become key targets for drug design, with more than 2,500 clinical trials currently under way. This review summarizes the essential features of angiogenesis and discusses therapeutic strategies that have been applied to specific diseases known to be associated with perturbation of normal angiogenic control.
Copyright © 2010 SIR. Published by Elsevier Inc. All rights reserved.
Similar articles
-
[Angiogenesis and antiangiogenic cancer therapy].Vnitr Lek. 2004 Dec;50(12):930-8. Vnitr Lek. 2004. PMID: 15717808 Review. Czech.
-
Current strategies and future directions of antiangiogenic tumor therapy.Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003 Oct;35(10):873-80. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai). 2003. PMID: 14515202 Review.
-
Perspectives on lymphangiogenesis and angiogenesis in cancer.J Surg Oncol. 2011 May 1;103(6):484-8. doi: 10.1002/jso.21808. J Surg Oncol. 2011. PMID: 21480240 Review.
-
Angiogenesis--a new target for future therapy.Vascul Pharmacol. 2006 May;44(5):265-74. doi: 10.1016/j.vph.2006.01.005. Epub 2006 Mar 20. Vascul Pharmacol. 2006. PMID: 16545987 Review.
-
Angiogenic targets for potential disorders.Fundam Clin Pharmacol. 2011 Feb;25(1):29-47. doi: 10.1111/j.1472-8206.2010.00814.x. Fundam Clin Pharmacol. 2011. PMID: 20199582 Review.
Cited by
-
Venous endothelial injury in central nervous system diseases.BMC Med. 2013 Oct 11;11:219. doi: 10.1186/1741-7015-11-219. BMC Med. 2013. PMID: 24228622 Free PMC article. Review.
-
Human Hematopoietic Signal peptide-containing Secreted 1 (hHSS1) modulates genes and pathways in glioma: implications for the regulation of tumorigenicity and angiogenesis.BMC Cancer. 2014 Dec 6;14:920. doi: 10.1186/1471-2407-14-920. BMC Cancer. 2014. PMID: 25481245 Free PMC article.
-
Anti-Angiogenic Effect of Asperchalasine A Via Attenuation of VEGF Signaling.Biomolecules. 2019 Aug 12;9(8):358. doi: 10.3390/biom9080358. Biomolecules. 2019. PMID: 31408989 Free PMC article.
-
Inhibition of angiogenesis in endothelial cells by Human Lysyl oxidase propeptide.Sci Rep. 2018 Jul 11;8(1):10426. doi: 10.1038/s41598-018-28745-8. Sci Rep. 2018. PMID: 29993014 Free PMC article.
-
Portal Vein Embolization: Impact of Chemotherapy and Genetic Mutations.J Clin Med. 2017 Mar 1;6(3):26. doi: 10.3390/jcm6030026. J Clin Med. 2017. PMID: 28257031 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
