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Case Reports
. 2010 Sep;2(3):122-4.
doi: 10.4103/0974-7796.68862.

Primary renal adenosquamous carcinoma

Mohammad Ashik Zainuddin  1 , Tan Yeh Hong
Affiliations
Case Reports

Primary renal adenosquamous carcinoma

Mohammad Ashik Zainuddin et al. Urol Ann. 2010 Sep.

Abstract

A case of renal adenosquamous carcinoma is presented. The fact that the urothelium has no glandular or squamous structures makes the pathogenesis of this tumor unique. The process is assumed to begin with urothelial metaplasia resulting from chronic irritation leading to dysplasia and subsequently squamous and glandular differentiation.

Keywords: Adenosquamous carcinoma; metaplasia; renal.

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Conflict of interest statement

Conflict of Interest: None

Figures

Figure 1
Figure 1
CT scan of the kidneys demonstrating large lower pole heterogenous mass with perirenal fat stranding
Figure 2
Figure 2
Chest radiograph taken 3 months postoperatively showing lung metastasis and a moderate left pleural effusion. Preoperative chest radiograph was normal
Figure 3
Figure 3
Microscopic view of tumor specimen demonstrating pleiomorphism and two keratin whorls, suggestive of differentiation towards a squamous cell carcinoma (H and E stain, ×100)
Figure 4
Figure 4
Microscopic view of the same tumor specimen showing malignant cells adopting a glandular architecture.(H and E stain, ×100)
See this image and copyright information in PMC

References

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