Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975;41(3):249-56.
doi: 10.1007/BF02565060.

Regulation of citrate synthase activity of Saccharomyces cerevisiae

J S Coleman, J K Bhattacharjee

Regulation of citrate synthase activity of Saccharomyces cerevisiae

J S Coleman et al. Antonie Van Leeuwenhoek. 1975.

Abstract

Citrate synthase activity of Saccharomyces cerevisiae was determined by a radioactive assay procedure and the reaction product, 14C-citric acid, was identified by chromatographic techniques. ATP, d-ATP, GTP and NADH were most inhibitory to the citrate synthase invitro. The activity was inhibited to a lesser extent by ADP, UTP, and NADP whereas, AMP and CTP were much less inhibitory. NADH, like NAD, glutamic acid, glutamine, arginine, ornithine, proline, aspartic acid and alpha-ketoglutarate exhibited no inhibition. These results have been discussed in the light of the role of citrate synthase for the energy metabolism and glutamic acid biosynthesis.

PubMed Disclaimer

References

    1. Biochim Biophys Acta. 1970 Nov 24;222(2):290-8 - PubMed
    1. Science. 1956 May 11;123(3202):848 - PubMed
    1. Biochim Biophys Acta. 1966 Oct 17;128(1):190-2 - PubMed
    1. Biochem Z. 1964 Jun 16;339:501-13 - PubMed
    1. Biochim Biophys Acta. 1968 Jan 8;151(1):225-35 - PubMed

Publication types

MeSH terms