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. 1990;8(8-12):717-20.
doi: 10.1016/0731-7085(90)80109-3.

The application of Fourier-transform Raman spectroscopy to the analysis of pharmaceuticals and biomaterials

A M Tudor  1 , C D Melia, J S Binns, P J Hendra, S Church, M C Davies
Affiliations

The application of Fourier-transform Raman spectroscopy to the analysis of pharmaceuticals and biomaterials

A M Tudor et al. J Pharm Biomed Anal. 1990.

Abstract

Near infrared Fourier-transform (FT) Raman spectroscopy is shown to be a useful spectroscopic tool for the molecular structural analysis of drugs and biomedical polymers. The technique has been applied to the non-invasive investigation of the hydrolytic degradation of a biodegradable polymer in water over a period of 15 days and to the analysis of a drug within a polymer vehicle over a wide drug concentration range. This work demonstrates the potential value of FT Raman spectroscopy in the field of pharmaceutical science.

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