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. 1975;41(3):319-28.
doi: 10.1007/BF02565066.

Bacterial and fungal growth in total parenteral nutrition solutions,

Bacterial and fungal growth in total parenteral nutrition solutions,

M L Failla et al. Antonie Van Leeuwenhoek. 1975.

Abstract

The most serious complication of prolonged intravenous infusion of hypertonic dextrose and amino acids is infection. Frequently, the etiology is fungal rather than bacterial. Previous authors have suggested that bacterial survival and growth in the solutions is suppressed by (a) high dextrose concentration, (b) high osmolality, or (c) low pH. This paper presents evidence that proposals (a) and (b) are untenable and (c) is only partly responsible. We call attention to the presence of a factor that is antibacterial but not antifungal; namely, a high concentration of glycine.

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References

    1. Arch Surg. 1971 Dec;103(6):705-8 - PubMed
    1. Appl Microbiol. 1973 Dec;26(6):874-9 - PubMed
    1. N Engl J Med. 1974 Jun 20;290(25):1403-7 - PubMed
    1. Science. 1974 May 31;184(4140):952-6 - PubMed
    1. J Bacteriol. 1973 Nov;116(2):1029-53 - PubMed

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