doi: 10.1021/ja1081124.
Epub 2010 Oct 28.
Palladium-catalyzed aminosulfonylation of aryl halides
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- PMID: 21028814
- DOI: 10.1021/ja1081124
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Palladium-catalyzed aminosulfonylation of aryl halides
J Am Chem Soc.
.
Abstract
The palladium-catalyzed three-component coupling of aryl iodides, sulfur dioxide, and hydrazines to deliver aryl N-aminosulfonamides is described. The colorless crystalline solid DABCO·(SO(2))(2) was used as a convenient source of sulfur dioxide. The reaction tolerates significant variation of both the aryl iodide and hydrazine coupling partners.
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