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Review
. 2010 Nov;30(4):541-52, vii.
doi: 10.1016/j.iac.2010.08.007. Epub 2010 Sep 24.

New human rhinovirus species and their significance in asthma exacerbation and airway remodeling

E Kathryn Miller  1
Affiliations
Review

New human rhinovirus species and their significance in asthma exacerbation and airway remodeling

E Kathryn Miller. Immunol Allergy Clin North Am. 2010 Nov.

Abstract

Asthma is the most common chronic disease of childhood, affecting 10% to 15% of all children. Several different stimuli including allergens, tobacco smoke, certain drugs, and viral or bacterial infections are known to exacerbate asthma symptoms. Among these triggers, viruses are frequent inducers of asthma exacerbations, with human rhinoviruses being the most common in children and adults. This article describes the different species of this virus and their roles as major triggers of asthma exacerbations.

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Figures

Figure 1
Figure 1
Phylogenetic tree depicting relationships between known HRV serotypes and novel HRV. Previously known HRV serotypes are designated by ‘HRV’. Novel sequences identified in this study are designated by ‘RV’ and a black circle. The numbers in parentheses after the label of these sequences indicates how many additional specimens contained each virus. Novel sequences identified in recent studies are designated by ‘HRV’ and a grey circle.
See this image and copyright information in PMC

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