Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2010 Nov;78(10):953-5.
doi: 10.1038/ki.2010.283.

Parathyroid resistance to FGF23 in kidney transplant recipients: back to the past or ahead to the future?

Hirotaka Komaba  1 , Masahiro Koizumi, Masafumi Fukagawa
Affiliations
Free article
Comment

Parathyroid resistance to FGF23 in kidney transplant recipients: back to the past or ahead to the future?

Hirotaka Komaba et al. Kidney Int. 2010 Nov.
Free article

Abstract

Fibroblast growth factor 23 (FGF23) modulates the metabolism of minerals and vitamin D. In chronic kidney disease (CKD), this process is disturbed owing to decreased parathyroid expression of FGF23's receptor complex Klotho-FGF receptor 1. In this issue, Krajisnik and colleagues demonstrate that similar alterations occur in parathyroid glands from kidney transplant recipients in association with a decline in allograft function. Is it possible that these data can be extrapolated to general early-stage CKD patients?

PubMed Disclaimer

Comment on

MeSH terms

LinkOut - more resources