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Comment
. 2010 Nov;9(11):841.
doi: 10.1038/nrd3304. Epub 2010 Oct 29.

Cancer: Targeting mutant BRAF in metastatic melanoma

Alexandra Flemming
Comment

Cancer: Targeting mutant BRAF in metastatic melanoma

Alexandra Flemming. Nat Rev Drug Discov. 2010 Nov.
No abstract available

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Comment on

  • Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma.
    Bollag G, Hirth P, Tsai J, Zhang J, Ibrahim PN, Cho H, Spevak W, Zhang C, Zhang Y, Habets G, Burton EA, Wong B, Tsang G, West BL, Powell B, Shellooe R, Marimuthu A, Nguyen H, Zhang KY, Artis DR, Schlessinger J, Su F, Higgins B, Iyer R, D'Andrea K, Koehler A, Stumm M, Lin PS, Lee RJ, Grippo J, Puzanov I, Kim KB, Ribas A, McArthur GA, Sosman JA, Chapman PB, Flaherty KT, Xu X, Nathanson KL, Nolop K. Bollag G, et al. Nature. 2010 Sep 30;467(7315):596-9. doi: 10.1038/nature09454. Nature. 2010. PMID: 20823850 Free PMC article. Clinical Trial.

References

    1. Cancer Res. 2010 Jul 1;70(13):5518-27 - PubMed
    1. N Engl J Med. 2010 Aug 26;363(9):809-19 - PubMed
    1. Nature. 2010 Sep 30;467(7315):596-9 - PubMed

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