Review
Cellular and viral ligands that interact with the EGF receptor
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- PMID: 2103500
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Review
Cellular and viral ligands that interact with the EGF receptor
Semin Cancer Biol.
1990 Aug.
Abstract
The growth regulatory functions of a family of structurally related polypeptides are mediated through the membrane-bound epidermal growth factor receptor molecule. This ligand family includes epidermal growth factor, transforming growth factor-alpha, amphiregulin, and polypeptides encoded by several poxviruses. The structural and functional properties that are characteristic of the ligand family provide a basis for possible evolutionary relationships among the various ligands.
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