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Meta-Analysis
. 2010 Nov;197(5):350-6.
doi: 10.1192/bjp.bp.109.074526.

Early intervention services, cognitive-behavioural therapy and family intervention in early psychosis: systematic review

Victoria Bird  1 , Preethi Premkumar, Tim Kendall, Craig Whittington, Jonathan Mitchell, Elizabeth Kuipers
Affiliations
Meta-Analysis

Early intervention services, cognitive-behavioural therapy and family intervention in early psychosis: systematic review

Victoria Bird et al. Br J Psychiatry. 2010 Nov.

Abstract

Background: Early intervention services for psychosis aim to detect emergent symptoms, reduce the duration of untreated psychosis, and improve access to effective treatments.

Aims: To evaluate the effectiveness of early intervention services, cognitive-behavioural therapy (CBT) and family intervention in early psychosis.

Method: Systematic review and meta-analysis of randomised controlled trials of early intervention services, CBT and family intervention for people with early psychosis.

Results: Early intervention services reduced hospital admission, relapse rates and symptom severity, and improved access to and engagement with treatment. Used alone, family intervention reduced relapse and hospital admission rates, whereas CBT reduced the severity of symptoms with little impact on relapse or hospital admission.

Conclusions: For people with early psychosis, early intervention services appear to have clinically important benefits over standard care. Including CBT and family intervention within the service may contribute to improved outcomes in this critical period. The longer-term benefits of this approach and its component treatments for people with early and established psychosis need further research.

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Figures

Fig. 1
Fig. 1
Flow diagram of selection of papers for inclusion in the clinical review. CBT, cognitive–behavioural therapy; RCTs, randomised controlled trials. a. Includes RCTs published in multiple papers.
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