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. 2010 Jan;17(1):33-6.
doi: 10.4103/0971-6580.68348.

A Case of Intranasal Hemangioma and Concurrent Tetracycline-induced Ulcerative Gastritis in Dogs

H S Banga  1 , S Deshmukh, R S Brar, P D Gadhave, S G Chavhan, H S Sandhu
Affiliations

A Case of Intranasal Hemangioma and Concurrent Tetracycline-induced Ulcerative Gastritis in Dogs

H S Banga et al. Toxicol Int. 2010 Jan.

Abstract

Incidence of drug-induced gastritis and ulceration in human medicine is well established. Besides, unilateral hemangioma, a unique concurrent case of tetracycline induced gastric toxicity in a dog, characterized by gastritis and ulceration is being reported here. Grossly, the appearance of gastric ulcers mimicked the appearance of Italian pizza. Histological examination further supported drug-induced etiology in this case. This is probably the one of the few cases in the annals of veterinary medicine to be documented as drug-induced gastric toxicity in dog.

Keywords: Dogs; doxycycline; gastritis; histopathology; tetracyclines.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Nasal epistaxis
Figure 2
Figure 2
Gastric ulceration, a large reddish plaque-like growth with slightly raised outlines was appreciated besides congestion and thickening of wall of stomach
Figure 3
Figure 3
Cavernous hemangioma lesions attached to the nasal epithelium (H and E ×150)
Figure 4
Figure 4
Chronic ulcerative gastritis revealed complete replacement of mucosal lining by large areas of necrotic debris and marked destruction of gastric glands, fibroplasia (H and E ×150)
Figure 5
Figure 5
Chronic ulcerative gastritis with evidence of mucocele and with population of lymphomononuclear cells (H and E ×150)
Figure 6
Figure 6
The kidney revealed marked interstitial nephritis featured with many areas of mononuclear cell infiltration
See this image and copyright information in PMC

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