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. 2011 Jul;21(7):440-6.
doi: 10.1097/FPC.0b013e32833ffb56.

Doxorubicin pathways: pharmacodynamics and adverse effects

Caroline F Thorn  1 , Connie Oshiro, Sharon Marsh, Tina Hernandez-Boussard, Howard McLeod, Teri E Klein, Russ B Altman
Affiliations

Doxorubicin pathways: pharmacodynamics and adverse effects

Caroline F Thorn et al. Pharmacogenet Genomics. 2011 Jul.
No abstract available

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Figures

Fig. 1
Fig. 1
Graphical representation of the candidate genes involved in the pharmacodynamics of doxorubicin in a stylized cancer cell. A fully interactive version of this pathway is available online at PharmGKB at http://www.pharmgkb.org/do/serve?objId=PA165292163&objCls=Pathway. PK pathway, pharmacokinetics pathway; ROS, reactive oxygen species.
Fig. 2
Fig. 2
Graphical representation of the candidate genes involved in the cardiotoxicity of doxorubicin. A fully interactive version of this pathway is available online at PharmGKB at http://www.pharmgkb.org/do/serve?objId=PA165292164&objCls=Pathway. NO, nitrogen oxide; RNS, reactive nitrogen species; ROS, reactive oxygen species.
See this image and copyright information in PMC

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