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Review
. 2011 Feb;13(1):65-71.
doi: 10.1007/s11894-010-0154-8.

Idiosyncratic drug-induced liver injury: a clinical update

Haripriya Maddur  1 , Naga Chalasani
Affiliations
Review

Idiosyncratic drug-induced liver injury: a clinical update

Haripriya Maddur et al. Curr Gastroenterol Rep. 2011 Feb.

Abstract

Drug-induced liver injury (DILI) is a rare but potentially devastating adverse drug reaction. Its presentation can range from asymptomatic elevation in liver biochemistries to fulminant liver failure. Over the past decade, clinical and research interest in the field of idiosyncratic DILI has been intense, and several new findings have been reported. In this article, we provide an update on implicated agents, clinical features, outcomes, and the results of recently reported genetic studies.

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