Comment on

• Aortopathy is prevalent in relatives of bicuspid aortic valve patients.

  Biner S, Rafique AM, Ray I, Cuk O, Siegel RJ, Tolstrup K. Biner S, et al. J Am Coll Cardiol. 2009 Jun 16;53(24):2288-95. doi: 10.1016/j.jacc.2009.03.027. J Am Coll Cardiol. 2009. PMID: 19520254 Free PMC article.
• Bicuspid aortic valves with different spatial orientations of the leaflets are distinct etiological entities.

  Fernández B, Durán AC, Fernández-Gallego T, Fernández MC, Such M, Arqué JM, Sans-Coma V. Fernández B, et al. J Am Coll Cardiol. 2009 Dec 8;54(24):2312-8. doi: 10.1016/j.jacc.2009.07.044. J Am Coll Cardiol. 2009. PMID: 19958967
• Endothelial function, carotid-femoral stiffness, and plasma matrix metalloproteinase-2 in men with bicuspid aortic valve and dilated aorta.

  Tzemos N, Lyseggen E, Silversides C, Jamorski M, Tong JH, Harvey P, Floras J, Siu S. Tzemos N, et al. J Am Coll Cardiol. 2010 Feb 16;55(7):660-8. doi: 10.1016/j.jacc.2009.08.080. J Am Coll Cardiol. 2010. PMID: 20170792