FNAIT: the fetus pleads guilty!
- PMID: 21051565
- DOI: 10.1182/blood-2010-08-299404
FNAIT: the fetus pleads guilty!
Abstract
Fetal/neonatal alloimmune thrombocytopenia (FNAIT) resulting from fetal platelet destruction by maternal alloantibodies is the most common cause of severe fetal thrombocytopenia and of neonatal thrombocytopenia in maternity wards. The pathophysiology is largely unknown. The fetus has long been considered as an "innocent bystander."
Comment on
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Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy.Blood. 2010 Nov 4;116(18):3660-8. doi: 10.1182/blood-2010-05-284919. Epub 2010 Jul 20. Blood. 2010. PMID: 20647570
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