The effect of anti-inflammatory and antirheumatic drugs on inflammation in the rat
- PMID: 21056
- DOI: 10.1185/03007997709108968
The effect of anti-inflammatory and antirheumatic drugs on inflammation in the rat
Abstract
The anti-inflammatory effects of flurbiprofen and a number of other antirheumatic agents were studied in the rat using a model of inflammation, which involved the subcutaneous implantation of polyurethane cubes impregnated with an irritant. Results of acute and chronic studies indicated that flurbiprofen was extremely effective in suppressing both fluid and cellular phases of inflammation and, in this model, was comparable in potency to prednisolone.
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