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Review
. 2011 Feb;11(1):35-41.
doi: 10.1007/s11910-010-0155-x.

New information on the genetics of stroke

James F Meschia  1
Affiliations
Review

New information on the genetics of stroke

James F Meschia. Curr Neurol Neurosci Rep. 2011 Feb.

Abstract

Ischemic stroke, white matter hyperintensities related to small vessel ischemia, and intracranial aneurysms all show heritability. This review focuses on recent progress in understanding the molecular genetics of these disorders. Also reviewed is recent progress in understanding single-gene disorders in which stroke is a major feature of the phenotype, including CADASIL, CARASIL, hereditary angiopathy with nephropathy, aneurysm and muscle cramps, and Fabry disease and progress in pharmacogenomics as it relates to response to antiplatelet therapy.

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Conflict of interest statement

Disclosure No potential conflict of interest relevant to this article was reported.

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