[Detection of autoimmune lipoprotein--antibody complex in human plasma and aortic wall]
- PMID: 210589
[Detection of autoimmune lipoprotein--antibody complex in human plasma and aortic wall]
Abstract
An immune complex of lipoprotein-antibody was found in human blood plasma and in tissue liquid of aorta, impaired by atherosclerosis. In the majority of cases the antigen component of the immune complex was lipoprotein of very low density. After dissociation of the complex at acid pH, immunoglobulin G was isolated, which was identified by double immunodiffusion in agar gel; the immunoglobulin reacted in RBS both with autological and, in some cases, with isological lipoproteins.
Similar articles
-
[Isolation and identification of autoimmune lipoprotein-antibody complex from blood serum of rabbits with experimental atherosclerosis].Vopr Med Khim. 1975 Sep-Oct;21(5):526-31. Vopr Med Khim. 1975. PMID: 175569 Russian. No abstract available.
-
[Nature of the lipoprotein antigen responsible for the development of resistance to experimental atherosclerosis following its use in immunization of newborn rabbits].Vopr Med Khim. 1978 Jan-Feb;24(1):131-6. Vopr Med Khim. 1978. PMID: 208295 Russian.
-
[Effects of plasma very low density lipoprotein, low density lipoprotein and high density lipoprotein on platelet aggregation in endogenous hypertriglyceridemia].Sichuan Da Xue Xue Bao Yi Xue Ban. 2003 Oct;34(4):704-7. Sichuan Da Xue Xue Bao Yi Xue Ban. 2003. PMID: 14619587 Chinese.
-
[Immunological aspects of atherosclerosis].Klin Med (Mosk). 1989 Jan;67(1):27-37. Klin Med (Mosk). 1989. PMID: 2654462 Review. Russian. No abstract available.
-
[Atherogenesis and immune inflammation].Arkh Patol. 1995 May-Jun;57(3):6-14. Arkh Patol. 1995. PMID: 7677585 Review. Russian.
Cited by
-
Low density lipoprotein-containing circulating immune complexes: role in atherosclerosis and diagnostic value.Biomed Res Int. 2014;2014:205697. doi: 10.1155/2014/205697. Epub 2014 Jun 18. Biomed Res Int. 2014. PMID: 25054132 Free PMC article. Review.