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Comparative Study
. 1978 Jul-Aug;24(4):539-43.

[Detection of autoimmune lipoprotein--antibody complex in human plasma and aortic wall]

[Article in Russian]
A N Klimov, A D Denisenko, Iu N Zubzhitskiĭ, E A Gerchikova
  • PMID: 210589
Comparative Study

[Detection of autoimmune lipoprotein--antibody complex in human plasma and aortic wall]

[Article in Russian]
A N Klimov et al. Vopr Med Khim. 1978 Jul-Aug.

Abstract

An immune complex of lipoprotein-antibody was found in human blood plasma and in tissue liquid of aorta, impaired by atherosclerosis. In the majority of cases the antigen component of the immune complex was lipoprotein of very low density. After dissociation of the complex at acid pH, immunoglobulin G was isolated, which was identified by double immunodiffusion in agar gel; the immunoglobulin reacted in RBS both with autological and, in some cases, with isological lipoproteins.

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