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Comment
. 2010 Nov 16;107(46):E173-4; author reply E175.
doi: 10.1073/pnas.1010604107. Epub 2010 Nov 8.

Filtering data from high-throughput experiments based on measurement reliability

Willem Talloen, Sepp Hochreiter, Luc Bijnens, Adetayo Kasim, Ziv Shkedy, Dhammika Amaratunga, Hinrich Göhlmann
Comment

Filtering data from high-throughput experiments based on measurement reliability

Willem Talloen et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
Effect of increasing filtering stringency on the number of rejected null hypotheses for the fixed adjusted P value cutoff of α = 0.1. The threshold choice of I/NI calls, the point where signal exceeds noise, is indicated and corresponds with a filtering proportion of 73.6%.
See this image and copyright information in PMC

Comment on

References

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    1. Talloen W, et al. I/NI-calls for the exclusion of non-informative genes: A highly effective filtering tool for microarray data. Bioinformatics. 2007;23:2897–2902. - PubMed