Monocyclic phenolic acids; hydroxy- and polyhydroxybenzoic acids: occurrence and recent bioactivity studies
- PMID: 21060304
- PMCID: PMC6259451
- DOI: 10.3390/molecules15117985
Monocyclic phenolic acids; hydroxy- and polyhydroxybenzoic acids: occurrence and recent bioactivity studies
Abstract
Among the wide diversity of naturally occurring phenolic acids, at least 30 hydroxy- and polyhydroxybenzoic acids have been reported in the last 10 years to have biological activities. The chemical structures, natural occurrence throughout the plant, algal, bacterial, fungal and animal kingdoms, and recently described bioactivities of these phenolic and polyphenolic acids are reviewed to illustrate their wide distribution, biological and ecological importance, and potential as new leads for the development of pharmaceutical and agricultural products to improve human health and nutrition.
Figures
 
              
              
              
              
                
                
                 
              
              
              
              
                
                
                 
              
              
              
              
                
                
                 
              
              
              
              
                
                
                 
              
              
              
              
                
                
                 
              
              
              
              
                
                
                 
              
              
              
              
                
                
                 
              
              
              
              
                
                
                 
              
              
              
              
                
                
                 
              
              
              
              
                
                
                 
              
              
              
              
                
                
                 
              
              
              
              
                
                
                 
              
              
              
              
                
                
                 
              
              
              
              
                
                
                 
              
              
              
              
                
                
                References
- 
    - Martin K.R., Appel C.L. Polyphenols as dietary supplements: A double-edged sword. Nutr. Dietary Suppl. 2010;2:1–12.
 
- 
    - Harris C.S., Mo F., Migahed L., Chepelev L., Haddad P.S., Wright J.S., Willmore W.G., Arnason J.T., Bennett S.A.L. Plant phenolics regulate neoplastic cell growth and survival: a quantitative structure-activity and biochemical analysis. Can. J. Physiol. Pharmacol. 2007;85:1124–1138. doi: 10.1139/Y07-101. - DOI - PubMed
 
- 
    - Huang W.Y., Cai Y.Z., Zhang Y.B. Natural Phenolic Compounds From Medicinal Herbs and Dietary Plants: Potential Use for Cancer Prevention. Nutr. Cancer. 2010;62:1–20. - PubMed
 
- 
    - Liu R.H. Potential synergy of phytochemicals in cancer prevention: Mechanism of action. J. Nutr. 2004;134:3479S–3485S. - PubMed
 
Publication types
MeSH terms
Substances
LinkOut - more resources
- Full Text Sources
- Other Literature Sources
 
        