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Case Reports
. 2010 Sep 28;4(3):410-415.
doi: 10.1159/000321050.

Pancreatic and Gastric Plasmacytoma Presenting with Obstructive Jaundice, Diagnosed with Endoscopic Ultrasound-Guided Fine Needle Aspiration

Manmeet S Padda  1 , Tiffani Milless, Adebowale J Adeniran, Sepi Mahooti, Harry R Aslanian
Affiliations
Case Reports

Pancreatic and Gastric Plasmacytoma Presenting with Obstructive Jaundice, Diagnosed with Endoscopic Ultrasound-Guided Fine Needle Aspiration

Manmeet S Padda et al. Case Rep Gastroenterol. .

Abstract

Pancreatic plasmacytoma is a rare disorder which may present with obstructive jaundice. Only eighteen cases have been reported in the English language literature. We present the first case of pancreatic plasmacytoma and gastric plasmacytoma diagnosed with endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). A 75-year-old male with a known history of multiple myeloma presented with obstructive jaundice and a pancreatic mass. A concomitant gastric mass due to gastric plasmacytoma was seen. The diagnosis was established via EUS-FNA of the pancreatic mass. Pancreatic plasmacytoma should be suspected in patients with a history of myeloma. EUS-FNA is a safe and effective modality in the diagnosis of pancreatic plasmacytoma. Radiation therapy should be the first-line of therapy in treating pancreatic plasmacytomas.

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Figures

Fig. 1
Fig. 1
Endoscopic image of the ulcerated, raised gastric mass with adherent blood clot.
Fig. 2
Fig. 2
Gastric biopsy (H&E, high power magnification) with a diffuse infiltrate of plasmacytoid cells.
Fig. 3
Fig. 3
Endoscopic ultrasound image of a hypoechoic mass in the head of the pancreas with FNA needle within the mass (arrow).
Fig. 4
Fig. 4
EUS-FNA cytology of the pancreatic mass (PAP stain) showing a predominant monomorphic population of plasma cells.
See this image and copyright information in PMC

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