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Review
. 2010 Nov:1211:3-8.
doi: 10.1111/j.1749-6632.2010.05811.x.

Cell signaling

Jameel Iqbal  1 , Mone Zaidi, Narayan G Avadhani
Affiliations
Review

Cell signaling

Jameel Iqbal et al. Ann N Y Acad Sci. 2010 Nov.

Abstract

This review explores advances in our understanding of dynamicism in cellular signaling. Areas highlighted include the role of stochasticity in producing diversity in analogous signaling circumstances; population desynchronization's effect in masking newly appreciated repetitive bursts in protein phosphorylation and messenger RNA production; double-positive feedback interactions and their ability to synchronize multiple signal transduction pathways; scaffolding proteins control over signaling feedback; and frequency-responsive transcriptional regulation as an example of dynamicism in signaling.

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