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. 2010 Jul-Sep;55(3):225-8.
doi: 10.4103/0019-5154.70666.

Spectrum of non-infectious erythematous, papular and squamous lesions of the skin

Grace D' Costa  1 , Bhavana M Bharambe
Affiliations

Spectrum of non-infectious erythematous, papular and squamous lesions of the skin

Grace D' Costa et al. Indian J Dermatol. 2010 Jul-Sep.

Abstract

Background: Dermatopathologists base their diagnostic approach on the tissue reaction pattern. This study mainly includes the interpretation of two major tissue reaction patterns, the psoriasiform and the lichenoid reactions, with clinicopathological correlation.

Aims: To analyze the spectrum of non-infectious erythematous papular and squamous lesions of the skin at our institute, study the age, sex and anatomic distribution pattern and classify the lesions into major categories; determine the incidence of each subcategory.

Study period: two years; prospective, sample size: 161 cases, proforma filled.

Results: The lesions comprised 15.80% of the total load of surgical pathology and 30.99% of total number of skin biopsies. The highest percentage was in the 30-40 year age group (28.6%) with a male preponderance of 60.25%. The extremities were most frequently involved (67.79%). Lichenoid lesions were the commonest (46.57%) with lichen planus 26.7% and psoriasis vulgaris-19.88% being the most frequent. There were 5.6% seropositive cases. Correlation with the histopathological diagnosis was positive in 97.52% cases and negative in 2.48% cases.

Conclusion: The contribution of histopathology to the final diagnosis was significant. It confirmed the diagnosis in 92.55% and gave the diagnosis in 4.97% cases.

Keywords: Non-infectious; clinicopathological correlation; papulosquamous.

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Conflict of interest statement

Conflict of Interest: Nil.

Figures

Figure 1
Figure 1
Oral lichen planus - Shows plaque like, violaceous lesions over the buccal and glossal mucosa
Figure 2
Figure 2
Psoriasis - Shows erythematous and scaly lesions of the palms
Figure 3
Figure 3
Lichen planus - The epidermis shows hyperkeratosis, hypergranulosis, acanthosis and saw tooth rete ridges. Dermis shows a band like lymphocytic infiltrate touching the epidermis (H and E stain, ×40)
Figure 4
Figure 4
Psoriasis - Epidemis shows psoriasiform hyperplasia with markedly elongated rete ridges, with bulbous thickening and fusion of their lower portions with thin suprapapillary epidermal plates, edema and dilated vessels in the dermal papillae (H and E stain, ×40)
Figure 5
Figure 5
Classification of individual skin lesions
See this image and copyright information in PMC

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