O-GlcNAc and aging: C. elegans as a genetic model to test O-GlcNAc roles in type II diabetic insulin resistance
- PMID: 21068466
- PMCID: PMC3006014
- DOI: 10.18632/aging.100225
O-GlcNAc and aging: C. elegans as a genetic model to test O-GlcNAc roles in type II diabetic insulin resistance
Comment on
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Intracellular protein glycosylation modulates insulin mediated lifespan in C.elegans.Aging (Albany NY). 2010 Oct;2(10):678-90. doi: 10.18632/aging.100208. Aging (Albany NY). 2010. PMID: 20952811 Free PMC article.
References
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- Akimoto Y, et al. Elevation of the post-translational modification of proteins by O-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats. Glycobiology. 2007;17:127–140. - PubMed
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- Hanover JA. Glycan-dependent signaling: O-linked N-acetylglucosamine. FASEB J. 2001;15:1865–1876. - PubMed
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