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Review
. 2011 Feb;34(1):37-49.
doi: 10.1007/s00270-010-0012-y. Epub 2010 Nov 12.

Transcatheter arterial chemoembolization for liver cancer: is it time to distinguish conventional from drug-eluting chemoembolization?

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Review

Transcatheter arterial chemoembolization for liver cancer: is it time to distinguish conventional from drug-eluting chemoembolization?

Eleni Liapi et al. Cardiovasc Intervent Radiol. 2011 Feb.

Abstract

Conventional transcatheter arterial chemoembolization and chemoembolization with drug-eluting beads are increasingly being performed interchangeably in many institutions throughout the world. As both therapies continue to being tested in many phase II and III studies and in combination with other therapies, especially targeted agents, for treatment of primary and metastatic liver cancer, it is imperative to review their current status and evaluate their impact on patient survival. This review critically assesses patient selection, indications, contraindications, techniques, materials, safety, and clinical outcomes of patients treated with conventional chemoembolization and chemoembolization with drug-eluting beads.

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Conflict of interest statement

Conflict of interest Jean-Francois Geschwind: Consultancies in the last 3 years: BIOCOMPATIBLES, INC., BOSTON SCIENTIFIC, MDS NORDION, BIOSPHERE MEDICAL. Grants received in the last 3 years: GENENTECH, INC., BIOSPHERE MEDICAL, CON-TEXTVISION, INC., BOSTON SCIENTIFIC. Patents received: 20100203110 Therapeutics for Cancer Using 3-Bromopyruvate and Other Selective Inhibitors of ATP Production 08-12-2010; 201001 37434 Methods and compositions for administration of 3-halopyruvate and related compounds for the treatment of cancer 06-03-2010. Eleni Liapi: Employment: FEDERAL, THROUGH THE NIH T32 GRANT 5T32EB006351-02(PI: DEAN. F. WONG).

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