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Review
. 2011 Apr;36(3):242-7.
doi: 10.1111/j.1365-2230.2010.03941.x. Epub 2010 Nov 10.

Pyoderma gangrenosum: an Indian perspective

R M Bhat  1 , B Nandakishore, F F Sequeira, D Sukumar, G H Kamath, J Martis, S Furtado
Affiliations
Review

Pyoderma gangrenosum: an Indian perspective

R M Bhat et al. Clin Exp Dermatol. 2011 Apr.

Abstract

Background: Pyoderma gangrenosum (PG) is an uncommon, idiopathic, neutrophilic skin disease sometimes associated with systemic diseases. To our knowledge, there have been no case series of PG reported from India.

Aim: To study the clinical features, associated systemic diseases and treatment methods in our case series.

Methods: In total, 18 cases of PG diagnosed at our institution in Mangalore were evaluated in a prospective study.

Results: Ulcerative PG was the most common variant, seen in all except one case. Paediatric patients constituted less than a quarter (27.77%) of the patients. Systemic diseases were associated with the disease in over half of the patients (55.55%). The pathergy test was positive in seven patients (38.88%), and all but one had associated systemic disease. Corticosteroids were mainly used for management.

Conclusions: PG is a rare disease in India, but paediatric PG cases were relatively common. Ulcerative PG was the commonest type, and over half of the patients had associated systemic diseases. There were a significant number of patients with associated systemic disease who had a positive pathergy test.

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