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doi: 10.1016/j.str.2010.10.002.
An ATPase R-finger leaves its print on transcriptional activation
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- PMID: 21070936
- DOI: 10.1016/j.str.2010.10.002
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Comment
An ATPase R-finger leaves its print on transcriptional activation
Structure.
.
Free article
Abstract
Bacterial enhancer-binding proteins (bEBPs) are AAA+ ATPases that remodel σ⁵⁴-RNA polymerase holoenzyme for transcription. Chen et al., in this issue of Structure, show the R-finger, a conserved AAA+ arginine residue, drives structural changes that allow the ATP-bound bEBP to engage σ⁵⁴ en route to remodeling.
Copyright © 2010 Elsevier Ltd. All rights reserved.
Comment on
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Engagement of arginine finger to ATP triggers large conformational changes in NtrC1 AAA+ ATPase for remodeling bacterial RNA polymerase.Structure. 2010 Nov 10;18(11):1420-30. doi: 10.1016/j.str.2010.08.018. Structure. 2010. PMID: 21070941 Free PMC article.
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