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Review
. 2011;118(1):e15-20.
doi: 10.1159/000320891. Epub 2010 Nov 11.

Tuberous sclerosis complex renal disease

Bradley P Dixon  1 , John C Hulbert, John J Bissler
Affiliations
Review

Tuberous sclerosis complex renal disease

Bradley P Dixon et al. Nephron Exp Nephrol. 2011.

Abstract

Although not as common as other genetic renal diseases such as autosomal dominant polycystic kidney disease, patients with tuberous sclerosis complex frequently have significant renal involvement. Recent revelations in the cell biology of these renal disease manifestations as well as effective therapies for tuberous sclerosis complex-related renal issues have heralded hope of improved renal survival and improved quality of life for the TSC patient. This review specifically addresses some of the major renal manifestations of this disease.

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Figures

Fig. 1
Fig. 1
Important renal manifestations of TSC. a Polycystic renal disease demonstrated on the fast spin echo T2 fat-suppressed MRI. b Significant bilateral renal angiomyolipoma burden demonstrated on the CT scan with contrast. c Angiography reveals larger and proximal aneurysmal burden.
See this image and copyright information in PMC

References

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