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doi: 10.1016/j.cell.2010.10.036.
Shining a light on germinal center B cells
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- PMID: 21074042
- DOI: 10.1016/j.cell.2010.10.036
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Shining a light on germinal center B cells
Cell.
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Abstract
The mechanisms of B cell selection in lymphoid tissues are poorly understood. In this issue, Victora et al. (2010) use imaging of photoactivatable green fluorescent protein to define the movements of B cells in germinal centers and provide evidence that antibody affinity maturation is driven by competition for T cell help.
Copyright © 2010 Elsevier Inc. All rights reserved.
Comment on
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Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter.Cell. 2010 Nov 12;143(4):592-605. doi: 10.1016/j.cell.2010.10.032. Cell. 2010. PMID: 21074050 Free PMC article.
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